Working with Industry

Department of Chemistry University of Oxford

Prof Ed Anderson and Syngenta
Palladium-catalyzed cyclization of bromoenynamides to tricyclic azacycles: synthesis of trikentrin-like frameworks
Chemical Communications 2014, 50 (40), 5187-5189

Prof Hagan Bayley and Oxford Nanopore
Designing a Hydrophobic Barrier within Biomimetic Nanopores
Nano 2014, 8 (11), 11268-11279

Prof Paul Beer and Johnson Matthey
Halotriazolium Axle Functionalised [2]Rotaxanes for Anion Recognition: Investigating the Effects of Halogen-Bond Donor and Preorganisation
Chemistry-a European Journal 2014, 20 (37), 11740-11749 

Prof Gus Hancock, Prof Grant Ritchie, Oxford Children’s Hospital and Oxford Medical Diagnostics
Comparison of breath gases, including acetone, with blood glucose and blood ketones in children and adolescents with type 1 diabetes.
J. Breath Res. 2014, 8, 046010

Prof Michael Willis and AstraZeneca
Palladium-Catalyzed Synthesis of Ammonium Sulfinates from Aryl Halides and a Sulfur Dioxide Surrogate: A Gas- and Reductant-Free Process
Angew. Chem. Int. Ed. 2014, 53, 10204 –10208

Prof Mark Brouard, Prof Claire Vallance and Scientific Analysis Instruments (SAI Ltd)
Modifications to a commercially available linear mass spectrometer for mass-resolved microscopy with the pixel imaging mass spectrometry (PImMS) camera
Rapid Commun. Mass Spectrom. 2014, 28, 1649

Prof Michael Willis and Syngenta
DABSO-Based, Three-Component, One-Pot Sulfone Synthesis Org. Lett. 2014, 16, 150−153

Prof Steve Davies and AstraZeneca
Asymmetric syntheses of (–)-3-epi-fagomine, (2R,3S,4R)-dihydroxypipecolic acid and several polyhydroxylated homopipecolic acids
J. Org. Chem. 2014, 79, 10932

Prof Jonathan Burton and AstraZeneca
Cubanes in Medicinal Chemistry: Synthesis of Functionalized Building Blocks
Organic Letters 2014, 16 (16), 4094-4097

Prof Jonathan Burton and GSK
Diastereoselective Synthesis of Fused Lactone-Pyrrolidinones; Application to a Formal Synthesis of (-)-Salinosporamide A
Organic Letters 2014, 16 (16), 4078-4081

Prof Richard Compton and Schlumberger Cambridge Res Ltd
A flow system for hydrogen peroxide production at reticulated vitreous carbon via electroreduction of oxygen
Journal of Solid State Electrochemistry 2014, 18 (5), 1215-1221

Prof Stuart Conway, Prof Robert Paton, SGC and Pfizer-Neusentis
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-pi Interaction
Angewandte Chemie-International Edition 2014, 53 (24), 6126-6130

Prof Stuart Conway and Crysalin Ltd
Understanding the Structural Requirements for Activators of the Kef Bacterial Potassium Efflux System
Biochemistry 2014, 53 (12), 1982-1992

Prof Bill David, Rutherford Appleton Lab and Toyota Motor Co
Understanding composition property relationships in Ti-Cr-V-Mo alloys for optimisation of hydrogen storage in pressurised tanks
Physical Chemistry Chemical Physics 2014, 16 (31), 16563-16572

Prof Steve Davies and AstraZeneca
Asymmetric syntheses of (–)-3-epi-fagomine, (2R,3S,4R)-dihydroxypipecolic acid and several polyhydroxylated homopipecolic acids
Journal of Organic Chemistry 2014, 79 (22), 10932-10944

Prof Ben Davis, Prof Shabaz Mohammed, Prof James McCullagh and Pfizer
Synthetic Phosphorylation of p38 alpha Recapitulates Protein Kinase Activity Journal of the American Chemical Society 2014, 136 (5), 1698-1701

Prof Ben Davis and GlycoVaxyn AG
Rationally Designed Short Polyisoprenol-Linked PglB Substrates for Engineered Polypeptide and Protein N-Glycosylation
Journal of the American Chemical Society 2014, 136 (2), 566-569

Prof Ben Davis and UCB
Creation of a gated antibody as a conditionally functional synthetic protein
Nature Communications 2014, 5, Article No. 4388.

Prof Ben Davis and AstraZeneca
Dissecting the reaction of Phase II metabolites of ibuprofen and other NSAIDS with human plasma protein
Chemical Science 2014, 5 (10), 3789-3794

Prof Darren Dixon and AstraZeneca
One-Pot Asymmetric Nitro-Mannich/Hydroamination Cascades for the Synthesis of Pyrrolidine Derivatives: Combining Organocatalysis and Gold Catalysis
Catalysis 2014, 4 (2), 634-638

Prof Tim Donohoe and AstraZeneca
New methods for the synthesis of naphthyl amines; application to the synthesis of dihydrosanguinarine, sanguinarine, oxysanguinarine and (+/-)- maclekarpines B and C
Chemical Communications 2014, 50 (77), 11314-11316

Prof Tim Donohoe and AstraZeneca
De Novo Synthesis of Multisubstituted Aryl Amines Using Alkene Cross Metathesis
Organic Letters 2014, 16 (7), 1920-1923

Prof Tim Donohoe and GSK
Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation
Angewandte Chemie-International Edition 2014, 53 (52), 14555-14558

Prof George Fleet and Carbosynth Ltd
L-Fucose from Vitamin C with Only Acetonide Protection
Organic Letters 2014, 16 (21), 5663-5665

Prof Andrew Goodwin, Rutherford Appleton Lab and ESS AB
Spin correlations in Ca3Co2O6: Polarized-neutron diffraction and Monte Carlo study
Physical Review B 2014, 90 (1), Article No. 014411.

Prof Veronique Gouverneur and UCB
A General Copper-Mediated Nucleophilic F-18 Fluorination of Arenes
Angewandte Chemie-International Edition 2014, 53 (30), 7751-7755

Prof Veronique Gouverneur and Advion BioSyst
Diversity-Oriented Approach to CF3CHF-, CF3CFBr-, CF3CF2-, (CF3)(2)CH-, and CF3(SCF3)CH-Substituted Arenes from 1-(Diazo-2,2,2-trifluoroethyl)arenes
Organic Letters 2014, 16 (22), 6004-6007

Prof Veronique Gouverneur and F Hoffman La Roche Ltd
Anti-CD20 therapy down-regulates lesion formation and microglial activation in pattern I and pattern II rat models of multiple sclerosis
Journal of Neuroimmunology 2014, 275 (1-2), 1-2

Prof Veronique Gouverneur and GSK
A Comparison of the Behavior of Cu-64-Acetate and Cu-64-ATSM In Vitro and In Vivo
Journal of Nuclear Medicine 2014, 55 (1), 128-134

Prof Malcolm Green and Sud Chemied India Pvt Ltd
Deep hydrotreating of different feedstocks over a highly active Al2O3-supported NiMoW sulfide catalyst
Applied Catalysis a-General 2014, 475, 270-281

Prof Nicholas Green and Accelrys Inc
General master equation formulation of a reversible dissociation/association reaction 
Chemical Physics Letters 2014, 605, 44-46

Prof Gus Hancock, Prof Grant Ritchie and Oxford Medical Diagnostics Ltd
Laser-Based Method and Sample Handling Protocol for Measuring Breath Acetone
Analytical Chemistry 2014, 86 (12), 5838-5843 

Prof Shabaz Mohammed and Thermo Fisher Sci
Characterization and usage of the EASY-spray technology as part of an online 2D SCX-RP ultra-high pressure system
Analyst 2014, 139 (24), 6520-6528

Prof Mark Moloney and Virtua Drug
A Detailed Study of Antibacterial 3-Acyltetramic Acids and 3-Acylpiperidine-2,4-diones
Chemmedchem 2014, 9 (8), 1826-1837

Prof Jeremy Robertson and AstraZeneca
Substrate scope and stereocontrol in the Rh(II)-catalysed oxyamination of allylic carbamates
Tetrahedron 2014, 70 (40), 7388-7394 Article No. SI.

Prof Jeremy Robertson and AstraZeneca
Rhodium(II)-catalysed tandem aziridination and ring-opening: stereoselective synthesis of functionalised tetrahydrofurans
Chemical Communications 2014, 50 (77), 11393-11396

Prof Jeremy Robertson and Syngenta
Synthesis of Pandamarilactone-1
Organic Letters 2014, 16 (3), 884-887

Prof Edman Tsang, Diamond Light Source and Johnson Matthey
Interstitial modification of palladium nanoparticles with boron atoms as a green catalyst for selective hydrogenation
Nature Communications 2014, 5, Article No. 5787.

Prof Edman Tsang and SINOPEC
Tuning enantioselectivity in asymmetric hydrogenation of acetophenone and its derivatives via confinement effect over free-standing mesoporous palladium network catalysts
Journal of Catalysis 2014, 313, 113-126

Prof Edman Tsang and Johnson Matthey
Atomic Imaging of Carbon-Supported Pt, Pt/Co, and Ir@Pt Nanocatalysts by Atom-Probe Tomography
Catalysis 2014, 4 (2), 695-702

Prof Michael Willis and Pfizer-Neusentis
One-pot three-component sulfone synthesis exploiting palladium-catalysed aryl halide aminosulfonylation
Chemical Science 2014, 5 (1), 222-228