Working with Industry

Department of Chemistry University of Oxford

Prof Tom Brown and ATDBio
Reversible Energy-Transfer Switching on a DNA Scaffold
J. Am. Chem. Soc. 2015, 137 (7), 2444-2447

Prof Richard Compton and Micrux
Validating the geometry of interdigitated band electrodes: A variable scan rate study.
J. Electroanal. Chem. 2015, 748, 82-90

Prof Shabaz Mohammed and Thermo Fisher Scientific
Rapid Analyses of Proteomes and Interactomes Using an Integrated Solid-Phase Extraction Liquid Chromatography-MS/MS System
J. Proteome Res. 2015, 14 (2), 977-985

Dr Nick Green and BIOVIA
Reanalysis of Rate Data for the Reaction CH3 + CH3 -> C2H6 Using Revised Cross Sections and a Linearized Second-Order Master Equation
J. Phys. Chem. A 2015, 119 (28), 7668-7682

Prof Veronique Gouverneur, Advion BioSyst Inc and GE Healthcare
Oxidative fluorination of N-arylsulfonamides
J. Fluorine Chem. 2015, 180, 33-39

Prof Veronique Gouverneur and Advion BioSyst Inc
Synthesis of F-18-arenes from spirocyclic iodonium(III) ylides via continuous-flow microfluidics
J. Fluorine Chem. 2015, 178, 249-253

Prof Ed Anderson, Syngenta and AstraZeneca
Ynamide Carbopalladation: A Flexible Route to Mono-, Bi- and Tricyclic Azacycles
Chem. Eur. J. 2015, 21 (36), 12627-12639

Dr Tiancun Xiao and Guangzhou Boxabio Technol Ltd
Advances in the Study of the Antiatherogenic Function and Novel Therapies for HDL
Int. J. Mol. Sci. 2015, 16 (8), 17245-17272

Prof Dermot O’Hare and SCG Chemicals Co
Tuneable ultra high specific surface area Mg/Al-CO3 layered double hydroxides
Dalton Trans. 2015, 44 (37), 16392-16398

Prof Darren Dixon and Promega Corp

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor
Angew. Chem. Int. Ed. 2015, 54 (21), 6217-6221

Prof Paul Beer and DSTL Porton Down
Contrasting anion recognition behaviour exhibited by halogen and hydrogen bonding rotaxane hosts
Org. Biomol. Chem. 2015, 13 (9), 2582-2587

Prof Steve Davies and Syngenta
Pinacolatoboron fluoride (pinBF) is an efficient fluoride transfer agent for synthesis of benzylic fluorides
Tetrahedron Lett. 2015, 56, 3373

Prof Steve Davies and AstraZeneca
Asymmetric syntheses of polysubstituted homoprolines and homoprolinols
Tetrahedron 2015, 71, 9131

Prof Steve Davies and AstraZeneca
Concise total asymmetric syntheses of (–)-fagomine, two of its epimers, and two seven-membered ring congeners
Tetrahedron 2015, 71, 7170

Prof Michael Willis and Syngenta
Combining organometallic reagents, the sulfur dioxide surrogate DABSO, and amines:  A one-pot prepration of sulfonamides, amenable to array synthesis
Angew. Chem. Int. Ed. 2015, 54, 1168-1171

Prof Peter Edwards and SINOPEC
Catalytic dehydrogenation of propane by carbon dioxide: a medium-temperature thermochemical process for carbon dioxide utilisation
Faraday Discuss. 2015, 183, 161-176

Prof Tom Brown and LGC
Synthesis and use of universal sequence probes in fluorogenic multi-strand hybridisation complexes for economical nucleic acid testing
Mol. Cell. Probes 2015, 29 (4), 228-236

Prof Tim Donohoe and GSK
Strategic Application and Transformation of ortho-Disubstituted Phenyl and Cyclopropyl Ketones To Expand the Scope of Hydrogen Borrowing Catalysis
J. Am. Chem. Soc. 2015, 137 (50), 15664-15667

Prof Angela Russell, Prof Steve Davies and Summit
Second-generation compound for the modulation of utrophin in the therapy of DMD​
Hum. Mol. Genet. 2015, doi: 10.1093/hmg/ddv154

Prof Mark Moloney and GSK
Uncatalysed diaryldiazo cyclopropanations on bicyclic lactams: access to annulated prolines
Org. Biomol. Chem. 2015, 13 (23), 6522-6550

Prof David Hodgson and Novartis
Amine Protection/alpha-Activation with the tert-Butoxythiocarbonyl Group: Application to Azetidine Lithiation-Electrophilic Substitution
Organic Letters 2015, 17 (2), 330-333

Dr Tiancun Xiao and Guangzhou Boxabio Technol Ltd
Anti-Obese Effect of Glucosamine and Chitosan Oligosaccharide in High-Fat Diet-Induced Obese Rats
Mar. Drugs 2015, 13 (5), 2732-2756

Prof David Hodgson, Rob Paton, Tim Claridge and Novartis
α- and α-Lithiation–Electrophile Trapping of N-Thiopivaloyl and N-tert-Butoxythiocarbonyl α-Substituted Azetidines: Rationalization of the Regiodivergence Using NMR and Computation.
J. Org. Chem. 2015, 80 (20), 9838–9846

Prof Edman Tsang and Johnson Matthey
Dual doping effects (site blockage and electronic promotion) imposed by adatoms on Pd nanocrystals for catalytic hydrogen production
Chem. Commun. 2015, 51 (1), 46-49

Dr Roel Dullens, Prof Dirk Aarts and InProcess-LSP
Microscopic dynamics of synchronization in driven colloids
Nat. Commun. 2015, 6, Article No. 7187.

Prof George Fleet, BioApply and Phytoquest Ltd
Isolation and SAR studies of bicyclic iminosugars from Castanospermum australe as glycosidase inhibitors
Phytochem. 2015, 111, 124-131

Prof George Fleet and Phytoquest Ltd
Design and Synthesis of Labystegines, Hybrid Iminosugars from LAB and Calystegine, as Inhibitors of Intestinal alpha-Glucosidases: Binding Conformation and Interaction for ntSI
J. Org. Chem. 2015, 80 (9), 4501-4515

Prof Veronique Gouverneur and Advion
F-18-Labeling of Aryl-SCF3, -OCF3 and -OCHF2 with [F-18]Fluoride
Angew. Chem. Int. Ed. 2015, 54 (34), 9991-9995

Prof Stephen Faulkner and Promega Corp
Development of an enzymatic pretargeting strategy for dual-modality imaging
Chem. Comm. 2015, 51 (19), 4055-4058

Prof Jeremy Robertson and Buker Daltonik
Unique metabolites protect earthworms against plant polyphenols
Nat. Commun. 2015, 6, Article No. 7869.

Prof Carol Robinson, Prof Martin Smith and Peptide Prot Res Ltd, Cambridge MedChem Consulting
Bifunctional crosslinking ligands for transthyretin
Open Biol. 2015, 5 (9), Article No. 150105.

Prof Paul Beer and Johnson Matthey
A halogen- and hydrogen-bonding [2]catenane for anion recognition and sensing
RSC Adv. 2015, 5 (12), 9298-9306

Prof Tom Brown, ATDBio and DSTL
Strain discrimination of Yersinia pestis using a SERS-based electrochemically driven melting curve analysis of variable number tandem repeat sequences
Chem. Sci. 2015, 6 (3), 1846-1852

Prof Tom Brown, ATDBio and DSTL
Using Surface-Enhanced Raman Spectroscopy and Electrochemically Driven Melting to Discriminate Yersinia pestis from Y. pseudotuberculosis Based on Single Nucleotide Polymorphisms within Unpurified Polymerase Chain Reaction Amplicons
Anal. Chem. 2015, 87 (3), 1605-1612

Prof Peter Edwards and ISIS Spallat Neutron & Muon Source
Questioning Antiferromagnetic Ordering in the Expanded Metal, Li(NH3)(4): A Lack of Evidence from mu SR
J. Phys. Chem. Lett. 2015, 6 (19), 3966-3970

Prof Tim Donohoe and Novartis
Hydrogen-Borrowing and Interrupted-Hydrogen-Borrowing Reactions of Ketones and Methanol Catalyzed by Iridium
Angew. Chem. Int. Ed. 2015, 54 (5), 1642-1645

Prof Justin Benesch, Prof Andrew Baldwin and Waters Corp
Combining tandem mass spectrometry with ion mobility separation to determine the architecture of polydisperse proteins
Int. J. Mass Spectrom. 2015, 377, 663-671 Article No. SI.

Prof Andrew Goodwin and DENSO CORP
Glass formation via structural fragmentation of a 2D coordination network
Chem. Commun. 2015, 51 (64), 12728-12731